1. What is the Pediatric MDRD Equation?

The Pediatric MDRD (Modification of Diet in Renal Disease) equation estimates glomerular filtration rate (GFR) in children using height and serum creatinine. It provides a simple yet effective method for assessing kidney function in pediatric patients.

2. How Does the Calculator Work?

The calculator uses the Pediatric MDRD equation:

Where:

• \( Height \) — Height in centimeters (cm)
• \( Scr \) — Serum creatinine in mg/dL

Explanation: The equation uses a constant factor of 0.41 multiplied by the ratio of height to serum creatinine to estimate GFR in pediatric patients.

3. Importance of Pediatric eGFR Calculation

Details: Accurate GFR estimation is crucial for diagnosing kidney disease in children, monitoring kidney function growth, and guiding appropriate medication dosing for pediatric patients.

4. Using the Calculator

Tips: Enter height in centimeters and serum creatinine in mg/dL. Both values must be positive numbers for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What age range is this equation appropriate for?
A: The Pediatric MDRD equation is typically used for children aged 1-18 years.

Q2: How does this differ from adult MDRD equations?
A: Pediatric MDRD is simplified and uses height as a key variable to account for body size differences in growing children.

Q3: What are normal eGFR values for children?
A: Normal eGFR values in children vary by age and body size but generally range from 90-140 mL/min/1.73m².

Q4: Are there limitations to this equation?
A: This equation may be less accurate in children with extremely high or low muscle mass or those with rapidly changing kidney function.

Q5: Should this be used for drug dosing in children?
A: While helpful for estimating kidney function, specific drug dosing should be based on comprehensive clinical assessment and possibly measured GFR in certain cases.