How To Calculate UACR

UACR Formula:

\[ UACR = \frac{\text{Urine Albumin (mg/dL)}}{\text{Urine Creatinine (g/dL)}} \]

UACR Result:

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1. What is UACR?

UACR (Urine Albumin-to-Creatinine Ratio) is a test that measures the amount of albumin (a protein) in the urine compared to the amount of creatinine. It's used to assess kidney function and detect early signs of kidney damage.

2. How Does the Calculator Work?

The calculator uses the UACR formula:

\[ UACR = \frac{\text{Urine Albumin (mg/dL)}}{\text{Urine Creatinine (g/dL)}} \]

Where:

Urine Albumin — Measured in milligrams per deciliter (mg/dL)
Urine Creatinine — Measured in grams per deciliter (g/dL)

Explanation: The ratio standardizes the albumin measurement by accounting for urine concentration, which varies throughout the day.

3. Importance of UACR Calculation

Details: UACR is a key marker for detecting early kidney disease, particularly in patients with diabetes or hypertension. It helps identify microalbuminuria, which is an early sign of kidney damage before significant decline in GFR occurs.

4. Using the Calculator

Tips: Enter urine albumin in mg/dL and urine creatinine in g/dL. Both values must be greater than zero. For accurate results, use first-morning urine samples when possible.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal UACR value?
A: Normal UACR is less than 30 mg/g. 30-300 mg/g indicates moderately increased albuminuria (formerly called microalbuminuria), and above 300 mg/g indicates severely increased albuminuria (macroalbuminuria).

Q2: How often should UACR be tested?
A: People with diabetes should be tested annually. Those with hypertension or other risk factors for kidney disease should be tested as recommended by their healthcare provider.

Q3: Can medications affect UACR results?
A: Yes, certain medications like ACE inhibitors and ARBs can reduce albuminuria. Always inform your doctor about all medications you're taking.

Q4: What factors can cause falsely elevated UACR?
A: Factors include urinary tract infection, fever, vigorous exercise, heart failure, and very high blood glucose levels.

Q5: How is UACR used in clinical practice?
A: UACR is used to screen for, detect, and monitor kidney disease. It helps guide treatment decisions and assess response to therapy in patients with chronic kidney disease.